Table 1 Baseline characteristics of patients recruited
Baseline characteristicsPlacebo (nā€Š=ā€Š7)Infliximab (nā€Š=ā€Š10)p Value
Age (years)58 (27 to 60)51 (37 to 62)0.669
Female, No (%)6 (85.7)8 (80.0)1.000
Disease duration (months)9 (5 to 11)8 (6 to 10)0.740
RF +ve, No (%)3 (42.9)7 (70.0)0.790
PISA score3 (1 to 6)4 (2 to 6)0.294
CCP +ve, No (%)4 (57.1)8 (80)1.000
EMS90 (15 to 120)60 (30 to 280)0.740
CRP23 (14 to 33)14.65 (5 to 52.25)0.669
SJC665 (3 to 9)7 (3 to 20.5)0.536
TJC683 (2 to 7)5 (2 to 13.5)0.408
HAQ score0.875 (0.750 to 1.875)1.187 (0.968 to 2.125)0.364
DAS284.30 (3.80 to 5.30)5.25 (3.23 to 6.48)0.669
Pain VAS43 (15 to 60)41 (0 to 85)0.807
Patient global VAS51 (23 to 67)55 (2 to 96)1.000
Physician global VAS38 (15 to 53)50 (2 to 65)0.140
Fatigue VAS51 (24 to 92)54 (0 to 90)0.732
  • Values are given as median (interquartile range).

  • No significant difference between the infliximab and placebo groups were observed for baseline measures.

  • CCP, cyclic citrullinated protein; CRP, C-reactive protein; DAS28, 28 joint Disease Activity Score; EMS, early morning stiffness; HAQ, Health Assessment Questionnaire; PISA, persistent inflammatory symmetrical arthritis; RF, rheumatoid factor; SJC66, number of swollen joints, of 66 joints assessed; TJC68, number of tender joints, of 68 joints assessed; VAS, visual analogue score along a 100 mm scale.