Table 6 Frequency distribution of items of selected domains of the SLICC Damage Index as a function of seizure occurrence in patients in the LUMINA cohort
Damage domains and items, %Seizuresp Value*
YesNo
n = 40n = 559
Renal
    Decreased glomerular filtration rate32.56.8<0.0001
    (<50%) (n = 51)
    Significant proteinuria (n = 85)37.512.5<0.0001
    End-stage renal disease (n = 32)30.03.4<0.0001
Neuropsychiatric
    Cognitive impairment (n = 126)30.020.2
    Stroke (n = 43)25.05.9<0.0001
    Cranial or peripheral neuropathy (n = 22)7.53.2
Musculoskeletal
    Muscle atrophy (n = 18)5.02.9
    Deforming arthritis (n = 22)5.03.6
    Osteoporosis (n = 20)7.53.0
    Osteonecrosis (n = 27)10.03.40.0591
    Osteomyelitis (n = 8)01.4

  • SLICC, Systemic Lupus International Collaborating Clinics; LUMINA, LUpus in MInorities NAture versus Nurture.

  • *Only p values ⩽0.05 are shown.