Relative change from baseline | 1 year (n = 26) | 3 year (n = 20) | 5 year (n = 15) |
mRSS | −39% (−86%; 59%) | −72% (−100%; 33%) | −73% (−100%; −25%) |
p*<10−3 | p*<10−3 | p*<10−3 | |
VC | 4% (−13%; 77%) | 3% (−32%; 93%) | −7% (−38%; 89%) |
p* = 0.019 | p* = 0.044 | p = 0.50 | |
TLC | 0 (−31%; 32%) | 1% (−42%; 66%) | −1% (−45%; 62%) |
p = 0.98 | p = 0.65 | p = 0.78 | |
FEV1 | 6% (−33%; 91%) | 6% (−28%; 100%) | −3% (−56%; 100%) |
p*<0.047 | p = 0.61 | p = 0.42 | |
DLCO | −4% (−43%; 53%) | −7% (−62%; 74%) | −9% (−59%; 64%) |
p = 0.09 | p = 0.31 | p = 0.41 |
mRSS, modified Rodnan Skin Score; VC, vital capacity; TLC, total lung capacity; FEV1, forced expiratory volume in first second; DLCO, carbon dioxide diffusion lung capacity. p*, paired Wilcoxon rank test p value.