Table 4 Relative changes (median, range) from baseline for the 26 systemic sclerosis (SSc) patients treated by autologous haematopoietic stem cell transplantation with at least 6 months follow-up after the procedure
Relative change from baseline1 year (n = 26)3 year (n = 20)5 year (n = 15)
mRSS−39% (−86%; 59%)−72% (−100%; 33%)−73% (−100%; −25%)
p*<10−3p*<10−3p*<10−3
VC4% (−13%; 77%)3% (−32%; 93%)−7% (−38%; 89%)
p* = 0.019p* = 0.044p = 0.50
TLC0 (−31%; 32%)1% (−42%; 66%)−1% (−45%; 62%)
p = 0.98p = 0.65p = 0.78
FEV16% (−33%; 91%)6% (−28%; 100%)−3% (−56%; 100%)
p*<0.047p = 0.61p = 0.42
DLCO−4% (−43%; 53%)−7% (−62%; 74%)−9% (−59%; 64%)
p = 0.09p = 0.31p = 0.41
  • mRSS, modified Rodnan Skin Score; VC, vital capacity; TLC, total lung capacity; FEV1, forced expiratory volume in first second; DLCO, carbon dioxide diffusion lung capacity. p*, paired Wilcoxon rank test p value.