Measure | 12 Weeks (n = 591) | 24 Weeks (n = 592) | 52 Weeks (n = 573) |
Composite indices | |||
DAS28 | 4.21 | 4.05 | 3.90 |
SDAI | 17.7 | 15.8 | 14.7 |
CDAI | 16.4 | 14.4 | 13.3 |
PAS | 3.46 | 3.40 | 3.40 |
Global scales | |||
Investigator global VAS | 26.0 | 22.0 | 21.0 |
Patient global VAS | 36.0 | 35.0 | 37.0 |
Joint pain VAS | 34.0 | 34.0 | 34.0 |
Fatigue VAS | 50.0 | 50.0 | 50.0 |
Functional measures | |||
MHAQ | 1.50 | 1.50 | 1.50 |
HAQ | 1.04 | 1.04 | 1.04 |
SF-36 | |||
Physical | 50.0 | 50.0 | 50.0 |
Bodily pain | 41.0 | 41.0 | 41.0 |
General health | 45.0 | 47.0 | 47.0 |
Vitality | 40.0 | 40.0 | 40.0 |
Social function | 75.0 | 62.5 | 75.0 |
Mental | 68.0 | 72.0 | 68.0 |
CDAI, Clinical Disease Activity Index; DAS28, 28-joint Disease Activity Score; HAQ, Health Assessment Questionnaire; MHAQ, modified Health Assessment Questionnaire; PAS, Patient Activity Scale; SDAI, Simplified Disease Activity Index; SF-36, Short Form-36; VAS, visual analogue scale (mm).