Table 3 Patient acceptable symptom state (PASS) cut-off points for composite indices and health status measures after 12, 24 and 52 weeks' treatment (75th centile approach)
Measure12 Weeks (n = 591)24 Weeks (n = 592)52 Weeks (n = 573)
Composite indices
Global scales
    Investigator global VAS26.022.021.0
    Patient global VAS36.035.037.0
    Joint pain VAS34.034.034.0
    Fatigue VAS50.050.050.0
Functional measures
    Bodily pain41.041.041.0
    General health45.047.047.0
    Social function75.062.575.0
  • CDAI, Clinical Disease Activity Index; DAS28, 28-joint Disease Activity Score; HAQ, Health Assessment Questionnaire; MHAQ, modified Health Assessment Questionnaire; PAS, Patient Activity Scale; SDAI, Simplified Disease Activity Index; SF-36, Short Form-36; VAS, visual analogue scale (mm).