Table 2 Patient acceptable symptom state (PASS) cut-off points for disease activity and health status measures after 24 weeks’ treatment
Measure75% (n = 945)ROC (n = 1496)Area under the curveSensitivity/specificity
Composite indices
Global scales
    Investigator global VAS23.019.00.7367/69
    Patient global VAS37.036.00.8374/75
    Joint pain VAS35.029.00.8068/76
    Fatigue VAS50.042.00.7168/66
Functional measures
    Bodily pain41.042.00.8065/81
    General health47.047.00.7676/65
    Social function62.575.00.7274/60
  • CDAI, Clinical Disease Activity Index; DAS28, 28-joint Disease Activity Score; HAQ, Health Assessment Questionnaire; MHAQ, modified Health Assessment Questionnaire; PAS, Patient Activity Scale; ROC, receiver operating characteristic; SDAI, Simplified Disease Activity Index; SF-36, Short Form-36; VAS, visual analogue scale (mm).