Measure | Baseline | 3 Months | 6 Months | 12 Months | p Value* |
RAMRIS synovitis (range 0–9) | 5.0 (3.0–6.0) | 5.0 (3.0–6.0) | 4.0 (3.0–5.0) | 4.0 (3.0–5.0) | <0.001 |
RAMRIS erosions (range 0–150) | 8.0 (5.0–11.0) | 8.5 (6.0–12.0) | 9.0 (5.0–12.0) | 9.0 (6.0–13.0) | <0.001 |
RAMRIS bone marrow oedema (range 0–45) | 2.0 (1.0–6.0) | 2.0 (1.0–4.0) | 2.0 (1.0–4.0) | 2.0 (1.0–4.0) | 0.03 |
MRI tenosynovitis (range 0–30) | 9.0 (6.0–11.0) | 8.0 (5.0–10.0) | 7.0 (5.0–9.0) | 7.0 (5.0–9.0) | 0.001 |
vdHSS erosions (range 0–160) | 1.0 (0.0–2.0) | 1.0 (0.0–3.0) | 1.0 (0.0–3.0) | 1.0 (0.0–3.0) | <0.001 |
vdHSS JSN (range 0–120) | 0.0 (0.0–2.0) | 0.0 (0.0–3.0) | 0.0 (0.0–4.0) | 0.0 (0.0–4.0) | 0.007 |
Total vdHSS (range 0–280) | 2.0 (0.0–5.0) | 2.0 (0.0–6.0) | 2.0 (0.0–7.0) | 2.0 (1.0–8.0) | <0.007 |
Results are shown as median (IQR).
*Wilcoxon signed ranks test.
JSN, joint space narrowing; MRI, magnetic resonance imaging; RAMRIS, rheumatoid arthritis magnetic resonance imaging score; vdHSS, van der Heijde modified Sharp score.