Table 2 Number and percentage of patients with real or no change of total score based on SDC and ROC based cut-offs
Cut-off levelSHSSENS
Reader (n)SHSSENSReal change, n (%)No change, n (%)Real change, n (%)No change, n (%)
1 (n = 251)SDC = 4.98SDC = 2.2826 (10.4)225 (89.6)23 (9.2)228 (90.8)
2*1*62 (24.7)189 (75.3)90 (35.9)161 (64.1)
2 (n = 189)SDC = 4.98SDC = 2.2820 (10.6)169 (89.4)10 (5.3)179 (94.7)
3*1*34 (18.0)155 (82.0)50 (26.5)139 (73.5)

  • SHS, Sharp–van der Heijde Score; SENS, Simplified Erosion Narrowing Score; SDC, smallest detectable change; n, number of patients.

  • *ROC-based cut-offs.