Non-responders (n = 42) | 30% Responders (n = 24) | 50% Responders (n = 26) | 70% Responders (n = 33) | p Value | |
Physician global assessment = 0 | 12/42 (28.6) | 5/24 (20.8) | 10/26 (38.5) | 18/33 (54.5) | 0.04* |
Active joint count = 0 | 13/42 (31.0) | 4/24 (16.7) | 7/26 (26.9) | 18/33 (54.5) | 0.02† |
Restricted joint count = 0 | 19/42 (45.2) | 8/24 (33.3) | 8/26 (30.8) | 18/33 (54.5) | 0.22 |
C-HAQ score = 0 | 11/24 (45.8) | 9/18 (50.0) | 10/18 (55.6) | 19/25 (76.0) | 0.15 |
ESR <20 mm/h | 27/42 (64.3) | 10/24 (41.7) | 18/26 (69.2) | 26/33 (78.8) | 0.03† |
Inactive disease‡ | 12/42 (28.6) | 4/24 (16.7) | 7/26 (26.9) | 18/33 (54.5) | 0.014† |
Values are number positive/number tested (%).
*Post-hoc analysis: p = 0.06.
†The percentage of patients with active joint count = 0, erythrocyte sedimentation rate <20 mm/h, and inactive disease is higher in 70% responders than in 30% responders (all p values = 0.02).
‡Defined according to CA Wallace et al.23
C-HAQ, Childhood Health Assessment Questionaire; ESR, erythrocyte sedimentation rate.