Table 1 Study breakdown from initial literature search
No. rejectedReasonTotal
Total identified508
171Not relevant337
29Not American College of Rheumatology criteria236
20Not clinical trials216
8No pain or function assessments189
5Follow-up data only184
4Fibromyalgia syndrome combined for analysis180
Eligible clinical trials
19Data recorded, but not given161
4Non-English language: translations reveal to be ineligible157
12Non-English language: translations not available145
+1Identified from bibliographies146
  • The 146 eligible clinical trials included 59 pharmacological and 87 non-pharmacological (including multidisciplinary). Studies were further subdivided into treatment interventions and the highest quality studies from each intervention were selected to be the basis for recommendations (table 2).