Table 1 Clinical and immunological characteristics in 50 SSc patients at the time of SRC
ParameterResults
Age at SRC diagnosis, years (mean (SD))53.3 (14.5)
Gender (female/male)37/13
SSc duration, months (mean (SD))27.7 (49.1) (median: 7.8)
RP, n (%)41/49 (91.8)
    Duration of RP, mo (mean (SD))68.3 (133.7) (median: 20.3)
    Type of SSc
    Diffuse cutaneous, n (%)43 (86)
Limited cutaneous, n (%)5 (10)
    Limited, n (%)2 (4)
    Organ involvement
    Interstitial lung disease, n (%)32/35 (91.4)
    Interstitial lung disease with restrictive syndrome, n (%)27/47 (57.4)
    Pulmonary arterial hypertension, n (%)2 (4)
    Left ventricular insufficiency, n (%)23 (46)
    Gastro-intestinal, n (%)42 (84)
        Oesophagus, n (%)39 (78)
        Bowel, n (%)8 (16)
    Other
        Arthralgia, n (%)43 (86)
        Arthritis, n (%)7 (14)
        Myalgias, n (%)15 (30)
        Myopathy, n (%)4 (8)
        Oedema, n (%)30 (60)
    Immunological tests
        Anti-nuclear Abs45 (90)
        Anti-topoisomerase 1 Abs14 (32)*
        Anti-centromere Abs0
  • *Values missing for 6 individuals.

  • Abs, antibodies; RP, Raynaud phenomenon; SRC, scleroderma renal crisis; SSc, systemic sclerosis.