All SSc patients (n = 570) | Diffuse SSc (n = 150) | Limited SSc (n = 420) | p Value | |
Males, n (%) | 86 (15) | 28 (19) | 58 (14) | 0.15 |
Age (years, mean (SD)) | 54 (13) | 53 (13) | 55 (13) | 0.12 |
Age at SSc diagnosis (years, mean (SD)) | 48 (14) | 45 (14) | 48 (14) | 0.03 |
Time since first non-Raynaud symptom (years, mean (SD)) | 9 (8) | 9 (8) | 8 (8) | 0.04* |
Rodnan score (mean (SD)) | 13 (11) | 25 (12) | 9 (5) | <0.001 |
Prior digital ulcer(s), n (%) | 302 (53) | 91 (61) | 211 (50) | 0.02 |
Calcium channel blockers, n (%) | 237 (42%) | 61 (41%) | 176 (42%) | 0.78 |
Anti hypertensive treatment, n (%) | 70 (12%) | 35 (23%) | 35 (8%) | <0.001 |
Peripheral vasodilators, n (%) | 78 (14%) | 18 (12%) | 60 (14%) | 0.48 |
Statistical tests: χ2 test or Fisher’s exact test, as appropriate, to compare diffuse and limited SSc for categorical variables; Student t test or ANCOVA adjusted to age for continuous variables (*). SSc, systemic sclerosis.