Patient | Age, sex | IgG APhL (GPL units) | IgM APhL (MPL units) | IgG β2GP1 (SG units) | IgM β2GP1 (SM units) | anti-HPF4 (OD 405) | SRA | APS events6 |
1. aPL+ | 28, F | 25 | >80 | 2 | 10 | 0.704 | + | Digital infarcts |
2. aPL+ | 35, F | 24 | >80 | 2 | >80 | 0.407 | – | Second trimester miscarriage |
3. aPL+ | 50, F | 24 | 2 | 21 | 1 | 0.646 | – | Arteriovenous fistula thromboses |
4. aPL+ | 41, F | 77 | >80 | 16 | >80 | 0.541 | – | Splenic infarcts |
5. aPL+ | 47, F | 15 | >80 | 3 | 61 | 0.729 | – | Renal thrombotic microangiopathy |
6. aPL+ | 42, F | 38 | 13 | 3 | 5 | 0.591 | – | Cerebrovascular accident |
7. aPL+ | 40, F | >80 | 61 | >80 | 78 | 0.740 | + | Cerebrovascular accident |
8. aPL– | 27, F | 10 | 19 | 2 | 4 | 0.606 | – | None |
9. aPL– | 38, F | 14 | 15 | 2 | 2 | 0.408 | – | None |
10. aPL– | 50, F | 7 | 5 | 2 | 2 | 0.428 | – | None |
11. aPL– | 21, M | 4 | 4 | 3 | 3 | 0.500 | – | None |
12. Control | 40, M | 18 | 36 | 4 | 11 | 0.650 | – | Unknown |
aPL+, aPL-positive SLE; aPL–, aPL-negative SLE.
aPL, antiphospholipid antibodies; APS, antiphospholipid syndrome; SLE, systemic lupus erythaematosus; SG, standard IgG; SM, standard IgM; SRA, serotonin release assay.