Table 1 Clinical manifestations and serum chemistry in female wild type (WT), transgenic low (TgL) and high (TgH) mice

	MRL/lpr 24W
	WT	TgL	TgH
Body weight, g	49.0 (6.10)	43.1 (4.40)	40.4 (3.00)
Spleen weight, g	1.31 (0.56)	0.90 (0.21)	0.33 (0.07)*
Total lymph node weight, g	6.14 (1.71)	3.43 (3.31)	1.51 (0.53)*
Urinary protein:creatinine ratio	17.4 (5.80)	15.98 (10.6)	5.24 (2.22)*
Serum protein, g/dl	6.83 (0.67)	6.93 (0.66)	7.68 (0.77)
Blood urea nitrogen, mg/dl	57.2 (24.9)	57.9 (19.2)	28.4 (6.00)*
Serum creatinine, mg/dl	0.27 (0.12)	0.20 (0.09)	0.36 (0.14)