Interaction of HLA-Cw6 with HLA-DRB1*07 in damaged and involved joints
| HLA-Cw6 | HLA-DRB1*07 | n (%) | Damaged joints OR (95% CI) | Involved joints OR (95% CI) | Tender joints OR (95% CI) | Swollen joints OR (95% CI) |
|---|---|---|---|---|---|---|
| +, presence of one or two alleles; −, absence of alleles. | ||||||
| p Value calculated using negative binomial regression analysis. | ||||||
| − | − | 317 (51.9) | Referent | Referent | Referent | Referent |
| + | − | 71 (11.6) | 0.96 (0.69 to 1.33) | 1.12 (0.87 to 1.44) | 1.46 (0.98 to 2.18) | 1.26 (0.83 to 1.90) |
| p = 0.82 | p = 0.37 | p = 0.07 | p = 0.28 | |||
| − | + | 78 (12.8) | 1.10 (0.79 to 1.54) | 1.21 (0.93 to 1.57) | 1.52 (1 to 2.31) | 1.07 (0.70 to 1.64) |
| p = 0.57 | p = 0.15 | p = 0.05 | p = 0.75 | |||
| + | + | 145 (23.7) | 0.59 (0.45 to 0.76) | 0.69 (0.56 to 0.84) | 1.02 (0.75 to 1.41) | 0.96 (0.69 to 1.33) |
| p = 0.02 | p<0.001 | p = 0.86 | p = 0.28 | |||