Baseline demographic and disease variables in the two treatment groups
| Methotrexate (n = 384) | Anti-TNF (n = 147) | p-Value | |
|---|---|---|---|
| Values are presented as mean (standard deviation of the mean) for continuous variables and as % for categorical variables. DMARDs, disease modifying anti-rheumatic drugs. | |||
| Age | 48.9 (13.2) | 46.0 (11.1) | 0.01 |
| Females | 49.7 | 40.8 | 0.07 |
| Disease duration, years | 5.8 (7.2) | 11.6 (9.3) | <0.001 |
| No. of previous DMARDs | 0.5 (0.8) | 2.6 (1.7) | <0.001 |
| Erosive disease | 27.8 | 56.3 | <0.001 |
| Rheumatoid factor positive | 5.9 | 6.4 | 0.83 |
| Investigator’s global assessment | 35.0 (15.2) | 44.8 (19.6) | <0.001 |