Geometric means of synovial mRNA levels before and after treatment with prednisolone or placebo
| Prednisolone (before treatment) | Prednisolone (after treatment) | Placebo (before treatment) | Placebo (after treatment) | |
|---|---|---|---|---|
| CI low, confidence interval lower limit; CI high, confidence interval upper limit. | ||||
| All values are expressed in relative expression units, normalised to glyceraldehyde-3-phosphate dehydrogenase (GADPH) message. | ||||
| IL1β | ||||
| Geometric mean | 0.001829 | 0.000993 | 0.001412 | 0.001479 |
| CI low | 0.000663 | 0.000485 | 0.000621 | 0.000668 |
| CI high | 0.005047 | 0.002034 | 0.003212 | 0.003276 |
| TNF | ||||
| Geometric mean | 0.349658 | 0.197523 | 0.277621 | 0.366998 |
| CI low | 0.126729 | 0.096473 | 0.122033 | 0.165688 |
| CI high | 0.964744 | 0.404419 | 0.631577 | 0.812898 |
| IL8 | ||||
| Geometric mean | 0.009089 | 0.004387 | 0.008108 | 0.012567 |
| CI low | 0.003294 | 0.002142 | 0.003564 | 0.005673 |
| CI high | 0.025077 | 0.008981 | 0.018446 | 0.027835 |
| MMP1 | ||||
| Geometric mean | 40.26167 | 3.861284 | 12.28034 | 33.79457 |
| CI low | 14.59228 | 1.88599 | 5.398034 | 15.25717 |
| CI high | 111.0863 | 7.905792 | 27.93737 | 74.85481 |