Number of deaths, mortality with standardised mortality ratios (SMRs) and SMR ratios using Swedish national data as reference population
| Variables | All (n = 1430) | At entry to study | SMR ratios (anti-TNF exposed vs. not exposed) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| As anti-TNF exposed (n = 921) | As not anti-TNF exposed (n = 652) | |||||||||
| All | Men (n = 211) | Women (n = 710) | All | Men (n = 178) | Women (n = 474) | All | Men | Women | ||
| pyrs, person years; SMR, standardised mortality ratio; TNF, tumour necrosis factor. | ||||||||||
| Results are shown for all subjects and also separately for those anti-TNF exposed and those not exposed by gender. SMRs and SMR ratios are presented with 95% CIs. | ||||||||||
| Deaths (31 Dec 2004) | 188 | 51 | 20 | 31 | 137 | 43 | 94 | — | — | — |
| Pyrs at risk (31 Dec 2004) | 7077 | 3177 | 726 | 2451 | 3900 | 1091 | 2809 | — | — | — |
| Crude mortality (per 1000 pyrs at risk) | 26.6 | 16.1 | 27.5 | 12.6 | 35.1 | 39.4 | 33.5 | — | — | — |
| SMRs and SMR ratios (after 2 years of follow-up) | 1.38 (0.98 to 1.78) | 1.20 (0.64 to 1.75) | 1.65 (0.57 to 2.74) | 0.94 (0.33 to 1.55) | 1.51 (0.99 to 2.04) | 1.18 (0.45 to 1.90) | 1.74 (1.01 to 2.47) | 0.79 (0.42 to 1.44) | 1.41 (0.51 to 4.04) | 0.54 (0.22 to 1.22) |
| SMRs and SMR ratios (after 3 years of follow-up) | 1.47 (1.13 to 1.80) | 1.20 (0.74 to 1.67) | 1.79 (0.85 to 2.72) | 0.88 (0.38 to 1.37) | 1.54 (1.11 to 1.96) | 1.24 (0.63 to 1.85) | 1.73 (1.15 to 2.31) | 0.78 (0.47 to 1.27) | 1.44 (0.65 to 3.16) | 0.50 (0.24 to 0.99) |
| SMRs and SMR ratios (after 4 years of follow-up) | 1.56 (1.26 to 1.86) | 1.50 (1.03 to 1.96) | 1.86 (1.00 to 2.72) | 1.29 (0.75 to 1.83) | 1.50 (1.14 to 1.86) | 1.19 (0.68 to 1.70) | 1.70 (1.21 to 2.19) | 1.00 (0.66 to 1.49) | 1.56 (0.78 to 3.05) | 0.76 (0.44 to 1.28) |