Frequencies of the MHC2TA (rs3087456/rs4774) haplotypes inferred in the Spanish cohorts
| HT | Patients with RA (2n = 700) | Patients with MS (2n = 792) | Patients with CD (2n = 646) | Patients with UC (2n = 726) | Controls(2n = 988) |
|---|---|---|---|---|---|
| CD, Crohn’s disease; HT, haplotype; MS, multiple sclerosis; RA, rheumatoid arthritis; UC, ulcerative colitis. | |||||
| Values are n (%). | |||||
| *OR (95% CI) = 0.7 (0.53 to 0.91); p = 0.006. | |||||
| †OR (95% CI) = 0.83 (0.63 to 1.04); p = 0.08. | |||||
| ‡OR (95% CI) = 1.6 (1.05 to 2.43); p = 0.019. | |||||
| §OR (95% CI) = 1.49 (0.98 to 2.24); p = 0.047. | |||||
| A/G | 404 (57.7) | 435 (55) | 353 (54.7) | 397 (54.8) | 544 (55) |
| A/C | 107 (15.3)* | 137 (17.3)† | 127 (19.6) | 152 (21) | 203 (20.5) |
| G/G | 135 (19.3) | 161 (20.3) | 136 (21.5) | 134(18.5) | 192 (19.4) |
| G/C | 54 (7.7)‡ | 57 (7.2)§ | 27 (4.2) | 42 (5.7) | 49 (4.9) |