Table 1

‚ÄÉCore set of variables to be assessed to define the involvement of each organ system17

DLCO, carbon dioxide diffusion lung capacity; FTP, finger tip distance; FVC, forced vital capacity; GI, gastrointestinal.
SkinModified Rodnan skin score
VesselsRaynaud
Digital ulcers (active/healed)
JointsFTP measurement
DAS 28 when synovitis occurs
TendonsNumber of tendon friction rubs at hands, wrists, elbows, knees, ankles
MusclesProximal weakness
Serum creatine phosphokinase
GI tractDysphagia, heartburn, early satiety, bloating, vomiting, diarrhoea, constipation, malabsorption, intestinal distension, barium oesophageal and intestinal x-ray
LungDyspnoea, lung fibrosis (chest x-ray)
Restrictive defect (by FVC, DLCO)
Pulmonary hypertension (by echo colour Doppler, DLCO)
HeartDyspnoea, palpitations, chest pain
Dizziness/presyncope/syncope
Heart rate, conduction defects, arrhythmias
Oedema/venous congestion
Pericardial effusion
Ejection fraction; E/A ratio
KidneyArterial pressure, serum creatinine, urinalysis