Ontology analysis of the genes that were expressed at significantly different levels between all 35 patients, or the subgroups consisting of 20 IFNhigh and 15 IFNlow patients, and healthy controls
All patients | IFNhigh | IFNlow | |
---|---|---|---|
Biological process | p Value | p Value | p Value |
NS, nonsignificant. | |||
Processes with a p value <0.05 were considered significant (with Bonferroni correction). | |||
Immunity and defence | 1.61E−11 | 3.41E−15 | NS |
Interferon-mediated immunity | 1.09E−06 | 3.38E−08 | NS |
Macrophage-mediated immunity | 6.83E−05 | 1.27E−04 | NS |
Lipid and fatty acid transport | 1.54E−04 | NS | NS |
Transport | 4.82E−04 | 3.33E−02 | NS |
Cytokine/chemokine-mediated immunity | 1.63E−03 | 2.61E−05 | NS |
Ligand-mediated signalling | 3.52E−03 | 1.92E−02 | NS |
Cell motility | NS | 4.24E−03 | NS |
Blood clotting | NS | 5.30E−03 | NS |
Oncogenesis | NS | 1.04E−02 | NS |
Cell structure and motility | NS | 1.55E−02 | NS |
Inhibition of apoptosis | NS | 1.66E−02 | NS |
Signal transduction | NS | 3.21E−02 | NS |
Proteolysis | NS | 3.97E−02 | NS |