Factors predicting occurrence of serious infection (all sites combined)
| Factor | Univariate | Multivariate |
|---|---|---|
| RR (95% CI) adjusted for age and sex | RR (95% CI) adjusted for age and sex | |
| DMARD, disease-modifying antirheumatic drug; HAQ, Health Assessment Questionnaire; RA, rheumatoid arthritis. | ||
| *Based on 93% complete data. | ||
| †Based on 94% complete data. | ||
| ‡Based on 68% complete data. | ||
| RA cumulative at 5th assessment: | ||
| Yes vs no | 1.8 (1.2 to 2.6) | 1.1 (0.6 to 2) |
| Rheumatoid factor* | ||
| Ever positive vs negative | 2.2 (1.5 to 3.4) | 2.0 (1.3 to 3.0) |
| Baseline smoking history† | ||
| Current or past vs never | 1.5 (1.0 to 2.4) | 1.2 (0.7 to 2.1) |
| Current only vs never | 1.7 (1.2 to 2.6) | 1.6 (1.0 to 2.5) |
| Steroid use | ||
| Ever vs never | 2.3 (1.6 to 3.5) | 2.2 (1.5 to 3.4) |
| DMARD use | ||
| Ever vs never | 1.3 (0.9 to 1.9) | 1.0 (0.6 to 1.6) |
| Erosive joints‡ | ||
| Ever vs never | 1.3 (0.9 to 1.9) | 1.0 (0.7 to 1.6) |
| Baseline HAQ | ||
| ⩾1 vs <1 | 1.0 (0.7 to 1.5) | 0.6 (0.3 to 1.1) |
| Five-year HAQ | ||
| ⩾1 vs<1 | 1.0 (0.7 to 1.5) | 1.2 (0.8 to 2.0) |
| Mean HAQ | ||
| ⩾1 vs <1 | 1.3 (0.9 to 1.8) | 1.9 (1.0 to 3.4) |