Mean change scores in HRQoL domains over 12 months as a function of different levels of change in clinical markers based on the ACR criteria
| Measure | PF | RP | BP | GH | VT | SF | RE | MH | PCS | MCS | HAQ | Fatigue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PF, physical functioning; RP, role physical; BP, bodily pain; GH, general health; VT, vitality; SF, social functioning; RE, role emotional; MH, mental health; PCS, physical component summary; MCS, mental component summary. | ||||||||||||
| *p<0.0001. | ||||||||||||
| ACR 70 standard | 14.62 (0.81) | 16.13 (0.95) | 17.53 (0.75) | 10.47 (0.67) | 13.30 (0.80) | 12.65 (0.92) | 13.87 (1.27) | 10.61 (0.90) | 15.33 (0.67) | 10.48 (0.93) | −1.12 (0.04) | −41.42 (2.03) |
| ACR50 standard | 10.45 (0.88) | 12.47 (1.04) | 13.39 (0.82) | 7.63 (0.73) | 9.62 (0.87) | 10.81 (1.00) | 10.44 (1.39) | 7.87 (0.98) | 11.42 (0.73) | 8.16 (1.03) | −0.85 (0.05) | −35.06 (2.25) |
| ACR20 standard | 5.53 (0.73) | 6.54 (0.85) | 9.12 (0.67) | 5.54 (0.60) | 6.35 (0.72) | 7.38 (0.83) | 6.61 (1.14) | 5.10 (0.81) | 6.65 (0.60) | 5.78 (0.84) | −0.49 (0.04) | −22.89 (1.84) |
| Same (<20%) | 0.73 (0.66) | 1.90 (0.78) | 2.82 (0.61) | 1.79 (0.55) | 1.96 (0.66) | 1.94 (0.76) | 2.89 (1.04) | 1.45 (0.74) | 1.48 (0.55) | 2.24 (0.77) | −0.09 (0.04) | −4.00(1.67) |
| F-statistic | 65.89* | 51.89* | 85.46* | 36.10* | 43.86* | 32.06* | 16.60* | 22.91* | 95.04* | 17.03* | 119.76* | 79.36* |
| Relative validity | 0.55 | 0.43 | 0.71 | 0.30 | 0.37 | 0.27 | 0.14 | 0.19 | 0.79 | 0.14 | 1.00 | 0.66 |