Table 3 Changes from baseline in composite status measure scores when patients achieved ACRnone/20/50/70 responses
Change from baseline in status measure scorep Value*
None (n = 87)ACR20 (n = 46)ACR50 (n = 36)ACR70 (n = 54)
Das44/ESR-4 item0.8 (1.20) (−1.29–3.91)2.30 (0.97) (0.62–5.26)p = 0.17†2.59 (0.92) (0.82–4.87)p = 0.001‡3.43 (1.28) (1.18–7.82)<0.001
Das44/ESR-3 item0.8 (1.24) (−1.32–3.91)2.08 (0.95) (0.56–5.03)p = 0.17†2.36 (0.88) (0.81–4.61)p = 0.002‡3.12 (1.22) (1.09–7.13)<0.001
DAS44/CRP-4 item0.75 (1.13) (−1.47–3.69)2.13 (0.90) (0.36–5.1)p = 0.07†2.50 (0.85) (0.88–4.68)p = 0.001‡3.29 (1.33) (0.91–7.92)<0.001
DAS44/CRP-3 item0.75 (1.17) (−1.52–3.72)1.92 (0.88) (0.4–4.85)p = 0.07†2.27 (0.80) (0.67–4.41)p = 0.002‡2.97 (1.25) (0.68–7.22)<0.001
DAS28/ESR-4 item0.75 (1.40) (−3.21–4.04)2.43 (1.20) (−0.14–4.99)p = 0.42†2.65 (1.22) (0.05–5.4)p = 0.001‡3.67 (1.05) (1.56–6.38)<0.001
DAS28/ESR-3 item0.70 (1.47) (−3.6–4.22)2.14 (1.13) (−0.18–4.84)p = 0.47†2.34 (1.21) (−0.58–5.29)p = 0.004‡3.22 (1.05) (1.01–5.89)<0.001
DAS28/CRP-4 item0.64 (1.21) (−2.55–3.68)2.05 (1.10) (−0.38–4.76)p = 0.12†2.42 (0.98) (0.5–4.67)p = 0.001‡3.31 (1.06) (1.21–6.49)<0.001
DAS28/CRP- 3 item0.59 (1.34) (−3.04–3.92)1.82 (1.08) (−0.31–4.82)p = 0.12†2.17 (0.94) (0.62–4.62)p = 0.004‡2.96 (1.01) (1.13–5.63)<0.001
SDAI8.41 (13.27) (−21–41.5)25.16 (12.74) (0.8–56.6)p = 0.12†29.95 (13.39) (2.3–58.6)p = 0.04‡36.79 (17.01) (12.1–78)<0.001
CDAI8.42 (14.27) (−20.5–51.8)23.62 (12.38) (1.3–52.6)p = 0.11†28.41 (13.40) (1.6–57.3)p = 0.05‡34.53 (15.71) (11.4–73.3)<0.001
  • ACR, American College of Rheumatology; CDAI, Clinical Disease Activity Index; CRP, C-reactive protein; DAS, Disease Activity Score; ESR, Westergren erythrocyte sedimentation rate; SDAI, Simplified Disease Activity Index.

  • Values are mean (SD) (range).

  • *ACRnone vs ACR20 vs ACR50 vs ACR70; ACRnone differs from all the other groups, p<0.05; analysis of variance.

  • †ACR20 vs ACR50.

  • ‡ACR50 vs ACR70.