Table 3 Effect of IgG-APS on tissue factor (TF) activity in carotid artery homogenates of LPS−/− and LPS+/+ mice
MiceTreatmentMean (SD) TF activity(pM/mg protein)
LPS+/+IgG-APS-117.0 (2.0)†
LPS+/+IgG-NHS1.0 (0.9)
LPS−/−IgG-APS-12.3 (1.2)*

  • LPS, lipopolysaccharide; APS, antiphospholipid syndrome; NHS, normal healthy serum.

  • *p = 0.0001 vs LPS+/+ mice treated with IgG-APS-1.

  • †p = 0.002 vs LPS+/+ mice treated with IgG-NHS.