Table 2 Distribution (%) of PTPN22 1858T allele carriers among controls and patients with RA

	1858T carriers	OR (95% CI)	p Value
Controls (n = 555)	21.4
Patients
All (n = 221)	34.4	1.92 (1.36 to 2.71)	0.0002
RF+ (n = 101)	39.6	2.41 (1.54 to 3.75)	0.0001
RF− (n = 114)	29.8	1.57 (1.00 to 2.44)	0.05
Anti-CCP+ (n = 129)	38.0	2.25 (1.50 to 3.37)	0.00009
Anti-CCP− (n = 86)	29.1	1.51 (0.92 to 2.49)	0.1

CCP, cyclic citrullinated peptide; PTPN22, protein tyrosine phosphatase N22; RA, rheumatoid arthritis; RF, rheumatoid factor.