Table 1 Outcome data of the Raynaud’s phenomenon diary*

	No. of RP attacks/day	Duration (minutes) RP attacks/day	Raynaud’s condition score/day	Outdoor temperature (°C)
Baseline	2.9 ± 1.9	62.3 ± 47.3	4.8 ± 2.6	2.7 ± 1.1
Week 8	1.8 ± 1.5^†	30.0 ± 8.7^†	3.6 ± 2.5^†	1.9 ± 1.9
Week 16	0.9 ± 1.2^†	11.6 ± 12.1^†	2.7 ± 2.1^†	11.9 ± 3.2^†
End of follow-up	1.2 ± 1.7^†	13.3 ± 13.7^†	3.0 ± 2.1^†	13.7 ± 3.2^†

RP, Raynaud’s phenomenon. *Data are presented as mean ± SD. ^†p<0.05 compared with baseline.