Table 3

 Incidence of lymphoma in RA patients29–32

StudyCountryNo. of patients with RAYears of follow up,mean (max)SIR for cancerSIR for lymphoma(odds ratio/RA activity level)
*As of 15 April 2005.
Gridley et al29Sweden11 6838.6 (20)1.02.0
Mellemkjaer et al30Denmark20 6997 (15)1.12.5
Isomaki et al31Finland46 1014.6 (7)1.12.7
Adalimumab 2005Global10 024*1.2 (7.7)1.063.19
1.0 (low)
Baecklund et al32Sweden11 6838.6 (20)5.4 (medium)
25.8 (high)