Table 1

 Adalimumab RA clinical safety database

PatientsExposure (PYs)
Act, Access to Therapy trial; PY, patient-years; ReAct, Research in Active RA trial.
US regulatory safety update,
31 August 2002
    Adalimumab24684870
    Placebo832365
Through 15 April 2005
    Open label extension studies25048047
        Act936208
        ReAct66104251
    Total10 05012 506