Table 1

 Immunohistochemical analysis of the study participants

No of patients, nNo of positive samples n (%)Median semiquantitative score(range)
IBD, inflammatory bowel disease; RA, rheumatoid arthritis.
*p<0.05 compared with controls, evaluated by Fisher’s exact test (comparisons of proportions) and Mann–Whitney test (comparisons of histological scores).
Qualitative and semiquantitative analysis for the presence of citrullinated proteins in inflamed and control tissues (semiquantitative evaluation: 0, no positive signal; 1, minimal presence of citrullination; 2, moderate amounts of citrullination; and 3, high degree of citrullination).
RA synovium1919 (100)*1.0 (0.5–3.0)*
Control synovium103 (30)0.0 (0.0–1.0)
IBD colonic biopsy specimens107 (70)0.5 (0.0–2.0)
Control colonic biopsy specimens104 (40)0.0 (0.0–2.0)
Polymyositis muscle biopsy specimens55 (100)*2.0 (1.0–3.0)*
Control muscle biopsy specimens70 (0)0.0 (0.0–0.0)
Chronic tonsillitis44 (100)1.5 (1.0–2.5)