Table 3

 Published studies on the effect of treatment on the cellular infiltrate and other biological variables in the synovial membrane

Drug treatmentCellular infiltrateCytokinesCell adhesion moleculesOther
Methotrexate8, 13, 14, 459, 13, 14, 42, 459, 13, 14, 45MMPs: 14, 45
Myeloid related proteins: 43
Leflunomide141414MMPs: 14
IM gold2, 44, 53
Corticosteroids7, 194, 76
TNF blockers10, 11, 17, 47, 5211, 1210, 52MMPs: 50
IL1 receptor antagonist1616