Variable | Before methotrexate | After methotrexate |
---|---|---|

Results are shown as mean (SD). | ||

*p<0.05 for the effect of methotrexate. p>0.1 for other variables. | ||

V_{max} values expressed as nmol/min/mg protein; K_{m} values expressed as μmol/l. | ||

Lymphocytes
| ||

V_{max} | 20.7 (5.6) | 16.2 (6.0)* |

K_{m} | 40.7 (2.9) | 38.3 (3.6) |

Erythrocytes
| ||

V_{max} | 100.9 (31.7) | 111.3 (42.3) |

K_{m} | 43.9 (6.9) | 42.6 (5.5) |