Table 3

 Adenosine deaminase activity

VariableBefore methotrexateAfter methotrexate
Results are shown as mean (SD).
*p<0.05 for the effect of methotrexate. p>0.1 for other variables.
Vmax values expressed as nmol/min/mg protein; Km values expressed as μmol/l.
Lymphocytes
Vmax20.7 (5.6)16.2 (6.0)*
Km40.7 (2.9)38.3 (3.6)
Erythrocytes
Vmax100.9 (31.7)111.3 (42.3)
Km43.9 (6.9)42.6 (5.5)