Comparison of the advantages/disadvantages of manual counting, semiquantitative, and digital image analysis techniques
| Advantages/disadvantages | MC | SQA | DIA |
|---|---|---|---|
| Observer bias | + | ++ | + |
| Field selection bias | ++ | − | − |
| Sensitivity to change | +++ | ++ | +++ |
| Time intensive | +++ | + | ++ |
| Cost | + | + | +++ |