Predictors of radiological progression at two years in patients with early rheumatoid arthritis
| Variable | Model 1* | Model 2† | ||
|---|---|---|---|---|
| OR (95% CI) | p Value | OR (95% CI) | p Value | |
| Variables remaining significant after backward stepwise logistic regression analyses including baseline values of anti-CCP antibodies/IgA-RF (yes/no), swollen joint count, ESR, Larsen score, shared epitope (yes/no), and therapeutic response at six months (yes/no). | ||||
| *The model included anti-CCP antibodies (yes/no), but not IgA-RF. | ||||
| †The model included IgA-RF (yes/no), but not anti-CCP antibodies. | ||||
| ‡EULAR response criteria, no v good/moderate response. | ||||
| Anti-CCP, antibodies to cyclic citrullinated peptide; CI, confidence interval; ESR, erythrocyte sedimentation rate; OR, odds ratio; RF, rheumatoid factor. | ||||
| Anti-CCP | 5.4 (1.7 to 17.0) | <0.01 | ||
| Swollen joints | 1.1 (1.0 to 1.2) | <0.05 | ||
| Therapeutic response‡ | 0.35 (0.14 to 0.85) | <0.05 | 0.41 (0.17 to 0.97) | <0.05 |
| IgA-RF | 9.8 (2.1 to 45.5) | <0.01 | ||
| ESR | 1.02 (1.00 to 1.04) | 0.05 | ||