Table 4

 Predictors of radiological progression at two years in patients with early rheumatoid arthritis

VariableModel 1*Model 2†
OR (95% CI)p ValueOR (95% CI)p Value
Variables remaining significant after backward stepwise logistic regression analyses including baseline values of anti-CCP antibodies/IgA-RF (yes/no), swollen joint count, ESR, Larsen score, shared epitope (yes/no), and therapeutic response at six months (yes/no).
*The model included anti-CCP antibodies (yes/no), but not IgA-RF.
†The model included IgA-RF (yes/no), but not anti-CCP antibodies.
‡EULAR response criteria, no v good/moderate response.
Anti-CCP, antibodies to cyclic citrullinated peptide; CI, confidence interval; ESR, erythrocyte sedimentation rate; OR, odds ratio; RF, rheumatoid factor.
Anti-CCP5.4 (1.7 to 17.0)<0.01
Swollen joints1.1 (1.0 to 1.2)<0.05
Therapeutic response‡0.35 (0.14 to 0.85)<0.050.41 (0.17 to 0.97)<0.05
IgA-RF9.8 (2.1 to 45.5)<0.01
ESR1.02 (1.00 to 1.04)0.05