Characteristics and (frequencies) of ROA among sibling pairs in the GARP study
| GARP study | Hip | Knee | Hand | Facet | DD | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| *p<0.05. | ||||||||||||
| †Numbers represent patients within GARP with ROA in at least one site at the specific joint location including subjects with unilateral and/or bilateral joint replacement (n = 38 for hip; n = 8 for knee). | ||||||||||||
| ‡Proportional ROA scores were made based on the number of joint sites with ROA at each location. ROA scores of joint replacements were scored as ROA absent. | ||||||||||||
| BMI, body mass index; DD, spinal disc degeneration; GARP, Genetics, Arthrosis and Progression study; HRT, hormone replacement therapy; ROA, radiological osteoarthritis. | ||||||||||||
| Characteristics† | 382 (1.0) | 115 (0.30) | 150 (0.40) | 301 (0.79) | 379 (0.99) | 344 (0.99) | ||||||
| ROA score 0 (freq)‡ | 293 (0.77) | 236 (0.62) | 162 (0.45) | 139 (0.39) | 118 (0.33) | |||||||
| ROA score 1 (freq)‡ | 60 (0.16) | 89 (0.23) | 106 (0.30) | 163 (0.45) | 170 (0.47) | |||||||
| ROA score 2 (freq)‡ | 29 (0.08) | 56 (0.15) | 93 (0.26) | 59 (0.16) | 73 (0.26) | |||||||
| Age (SD) | 60.3 (7.5) | 62.5 (7.7) | 61.8 (7.3) | 61.3 (7.4) | 60.3 (7.5) | 60.9 (7.4) | ||||||
| BMI (SD) | 27.0 (4.7) | 26.5 (3.9) | 28.1 (5.1)* | 27.0 (4.5) | 27.0 (4.7) | 27.2 (4.7) | ||||||
| Women (freq) | 312 (0.82) | 83 (0.27) | 122 (0.39) | 244 (0.78) | 309 (0.99) | 279 (0.89) | ||||||
| Postmenopausal no HTR | 252 (0.81) | |||||||||||