Association between autoantibodies and measures of inflammation (CRP, sPLA2, and the combination of CRP and sPLA2) at different points in time
B (95% CI) | |||
---|---|---|---|
CRP | sPLA2 | CRP + sPLA2 | |
IgM RF | |||
Inflammation 3 years earlier | 0.06 (−0.01 to 0.12) | 0.07 (0.04 to 0.10) | 0.18 (0.07 to 0.29) |
Inflammation 2 years earlier | 0.07 (0.01 to 0.13) | 0.05 (0.02 to 0.08) | 0.16 (0.06 to 0.25) |
Inflammation 1 year earlier | 0.12 (0.06 to 0.18) | 0.05 (0.01 to 0.08) | 0.19 (0.10 to 0.29) |
Inflammation at same point in time | 0.09 (0.04 to 0.13) | 0.07 (0.04 to 0.09) | 0.20 (0.13 to 0.27) |
Inflammation 1 year later | 0.06 (0.00 to 0.12) | 0.04 (0.02 to 0.07) | 0.15 (0.06 to 0.24) |
Inflammation 2 years later | 0.11 (0.05 to 0.16) | 0.02 (−0.01 to 0.04) | 0.14 (0.05 to 0.23) |
Inflammation 3 years later | 0.05 (−0.01 to 0.12) | 0.02 (−0.01 to 0.05) | 0.09 (−0.01 to 0.20) |
Anti-CCP | |||
Inflammation 3 years earlier | 0.05 (0.00 to 0.10) | −0.02 (−0.05 to 0.01) | 0.00 (−0.09 to 0.09) |
Inflammation 2 years earlier | 0.03 (−0.03 to 0.08) | −0.01 (−0.03 to 0.02) | 0.01 (−0.07 to 0.09) |
Inflammation 1 year earlier | 0.08 (0.03 to 0.13) | 0.00 (−0.03 to 0.03) | 0.08 (−0.01 to 0.16) |
Inflammation at same point in time | 0.05 (0.02 to 0.09) | 0.05 (0.02 to 0.07) | 0.13 (0.07 to 0.19) |
Inflammation 1 year later | 0.00 (−0.05 to 0.05) | 0.01 (−0.02 to 0.03) | 0.01 (−0.07 to 0.04) |
Inflammation 2 years later | 0.08 (0.03 to 0.14) | 0.02 (0.00 to 0.05) | 0.13 (0.04 to 0.21) |
Inflammation 3 years later | 0.06 (−0.01 to 0.13) | 0.01 (−0.02 to 0.05) | 0.09 (−0.01 to 0.19) |