Table 1

 Association between autoantibodies and measures of inflammation (CRP, sPLA2, and the combination of CRP and sPLA2) at different points in time

B (95% CI)
CRPsPLA2CRP + sPLA2
IgM RF
Inflammation 3 years earlier0.06 (−0.01 to 0.12)0.07 (0.04 to 0.10)0.18 (0.07 to 0.29)
Inflammation 2 years earlier0.07 (0.01 to 0.13)0.05 (0.02 to 0.08)0.16 (0.06 to 0.25)
Inflammation 1 year earlier0.12 (0.06 to 0.18)0.05 (0.01 to 0.08)0.19 (0.10 to 0.29)
Inflammation at same point in time0.09 (0.04 to 0.13)0.07 (0.04 to 0.09)0.20 (0.13 to 0.27)
Inflammation 1 year later0.06 (0.00 to 0.12)0.04 (0.02 to 0.07)0.15 (0.06 to 0.24)
Inflammation 2 years later0.11 (0.05 to 0.16)0.02 (−0.01 to 0.04)0.14 (0.05 to 0.23)
Inflammation 3 years later0.05 (−0.01 to 0.12)0.02 (−0.01 to 0.05)0.09 (−0.01 to 0.20)
Anti-CCP
Inflammation 3 years earlier0.05 (0.00 to 0.10)−0.02 (−0.05 to 0.01)0.00 (−0.09 to 0.09)
Inflammation 2 years earlier0.03 (−0.03 to 0.08)−0.01 (−0.03 to 0.02)0.01 (−0.07 to 0.09)
Inflammation 1 year earlier0.08 (0.03 to 0.13)0.00 (−0.03 to 0.03)0.08 (−0.01 to 0.16)
Inflammation at same point in time0.05 (0.02 to 0.09)0.05 (0.02 to 0.07)0.13 (0.07 to 0.19)
Inflammation 1 year later0.00 (−0.05 to 0.05)0.01 (−0.02 to 0.03)0.01 (−0.07 to 0.04)
Inflammation 2 years later0.08 (0.03 to 0.14)0.02 (0.00 to 0.05)0.13 (0.04 to 0.21)
Inflammation 3 years later0.06 (−0.01 to 0.13)0.01 (−0.02 to 0.05)0.09 (−0.01 to 0.19)