Baseline characteristics
| Sulfasalazine monotherapy (n = 58) | COBRA therapy (n = 52) | |||
|---|---|---|---|---|
| COBRA, Combinatietherapie Bij Reumatoide Artritis trial; RF, rheumatoid factor; SE, shared epitope. | ||||
| Age (years) (mean (SD)) | 49 (12) | 50 (13) | ||
| Disease duration (months) (mean (SD)) | 5 (5) | 5 (5) | ||
| Female (%) | 52 | 71 | ||
| RF positive (%) | 72 | 74 | ||
| Erosive disease (%) | 44 | 42 | ||
| SE (nil/heterozygous/ homozygous) (%) | 47/38/15 | 46/48/6 | ||