Table 3

‚ÄÉMost frequently reported treatment-emergent adverse events

Adverse event% of patientsEvents per patient-year*
*Open-label exposure.
Upper respiratory infection380.34
Accidental injury260.14
Injection-site reaction260.43
Flu syndrome210.11
Infection190.10
Rash170.09
Abdominal pain160.09
Pharyngitis150.08
Back pain150.08
Bronchitis150.10
Headache140.10
Rhinitis140.08
Diarrhoea130.07
Cough increased130.07
Arthralgia110.06
Hypertension110.05
Urinary tract infection110.07
Injection-site haemorrhages100.35