Most frequently reported treatment-emergent adverse events
| Adverse event | % of patients | Events per patient-year* |
|---|---|---|
| *Open-label exposure. | ||
| Upper respiratory infection | 38 | 0.34 |
| Accidental injury | 26 | 0.14 |
| Injection-site reaction | 26 | 0.43 |
| Flu syndrome | 21 | 0.11 |
| Infection | 19 | 0.10 |
| Rash | 17 | 0.09 |
| Abdominal pain | 16 | 0.09 |
| Pharyngitis | 15 | 0.08 |
| Back pain | 15 | 0.08 |
| Bronchitis | 15 | 0.10 |
| Headache | 14 | 0.10 |
| Rhinitis | 14 | 0.08 |
| Diarrhoea | 13 | 0.07 |
| Cough increased | 13 | 0.07 |
| Arthralgia | 11 | 0.06 |
| Hypertension | 11 | 0.05 |
| Urinary tract infection | 11 | 0.07 |
| Injection-site haemorrhages | 10 | 0.35 |