Histological scores of left ankles collected seven days after CFA injection
| DA (n = 5) | F344 (n = 5) | ACI (n = 5) | ||||
|---|---|---|---|---|---|---|
| Five rats per strain were randomly selected for histological analysis. | ||||||
| Values are means (SEM). Differences were not statistically significant. | ||||||
| CFA, complete Freund’s adjuvant; HMF, high power magnification field. | ||||||
| Inflammatory infiltrate (0–3) | 2.04 (0.35) | 2.56 (0.17) | 2.52 (0.16) | |||
| Synovial hyperplasia (0–3) | 1.40 (0.68) | 2.60 (0.24) | 2.60 (0.40) | |||
| Pannus (0–3) | 2.00 (0.32) | 1.40 (0.24) | 2.00 (0.32) | |||
| Fibrosis (0–3) | 0.80 (0.37) | 0.00 (0.00) | 0.00 (0.00) | |||
| Vessels/HMF | 7.28 (1.28) | 7.60 (2.37) | 8.80 (0.09) | |||
| Cartilage erosions (0–3) | 0.60 (0.40) | 1.20 (0.20) | 1.20 (0.20) | |||
| Bone erosions (0–3) | 1.40 (0.60) | 1.80 (0.37) | 2.20 (0.37) | |||