An overview of the response criteria
| PsARC | ACR criteria | EULAR criteria |
|---|---|---|
| ACR, American College of Rheumatology5; CRP, C reactive protein; DAS, Disease Activity Score7; ESR, erythrocyte sedimentation rate; EULAR, European League Against Rheumatism8; PhGA, physician global assessment; PsARC, psoriatic arthritis response criteria10; PtGA, patient global assessment; SJC, swollen joint count; TJC, tender joint count. | ||
| Response is defined by improvement in at least 2 of the 4 following measures, one of which must be joint swelling or tenderness, and no worsening in any of the 4 measures: PtGA of articular disease (1–5) and PhGA of articular disease (1–5): improvement = decrease by one category, worsening = increase by one category.Joint pain/tenderness score and joint swelling score: improvement = decrease by 30%, worsening = increase by 30%. | Improvement is defined by at least 20% improvement in TJC and in SJC, and at least 20% improvement in 3 of the 5 measures: ESR or CRP PhGA of disease activity PtGA of disease activity Patient assessment of pain Disability | A good response is defined as reaching a DAS ⩽2.4 or a DAS28 ⩽3.2 (“low” disease activity) in combination with an improvement >1.2 (twice the measurement error) in DAS or DAS28. A non-response is defined as an improvement ⩽0.6, and also as an improvement ⩽1.2 with a DAS>3.7 or DAS28>5.1 (“high” disease activity). All other possibilities are defined as a moderate response. |