Symptomatic radiographic knee OA present* | Symptomatic radiographic knee OA absent | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
ACR clinical criteria fulfilled* | ACR clinical criteria not fulfilled | ACR clinical criteria fulfilled† | ACR clinical criteria not fulfilled | Prevalence of symptomatic OA % (95% CI) | PPV% (95% CI) | NPV% (95% CI) | Sn% (95% CI) | Sp% (95% CI) | LR+ | LR− | |
ACR, American College of Rheumatology; LR+, likelihood ratio (positive); LR−, likelihood ratio (negative) (calculated using “symptomatic radiographic knee OA” as the disease and the “ACR criteria” as the test); NPV, negative predictive value; OA, osteoarthritis; PPV, positive predictive value; Sn, sensitivity; Sp, specificity. | |||||||||||
*Knee pain, aching or stiffness on most days in the past month and definite radiographic osteoarthritis in the index knee. | |||||||||||
†Tree-based criteria. | |||||||||||
All subjects | 105 | 154 | 133 | 396 | 33 (30 to 36) | 44 (38 to 51) | 72 (68 to 76) | 41 (35 to 47) | 75 (71 to 78) | 1.6 | 0.8 |
Men, 50–64 years | 16 | 36 | 22 | 89 | 32 (25 to 39) | 42 (28 to 58) | 71 (63 to 78) | 31 (20 to 45) | 80 (72 to 87) | 1.6 | 0.9 |
Men, ⩾65 years | 42 | 40 | 39 | 76 | 42 (35 to 49) | 52 (41 to 62) | 66 (57 to 74) | 51 (41 to 62) | 66 (57 to 74) | 1.5 | 0.7 |
Women, 50–64 years | 16 | 28 | 33 | 131 | 21 (16 to 27) | 33 (21 to 47) | 82 (76 to 88) | 36 (24 to 51) | 80 (73 to 85) | 1.8 | 0.8 |
Women, ⩾65 years | 31 | 50 | 39 | 100 | 37 (31 to 43) | 44 (33 to 56) | 67 (59 to 74) | 38 (28 to 49) | 72 (64 to 79) | 1.4 | 0.9 |
BMI <25 kg/m2 | 13 | 17 | 24 | 77 | 23 (17 to 31) | 35 (22 to 51) | 82 (73 to 88) | 43 (27 to 61) | 76 (67 to 84) | 1.8 | 0.7 |
BMI 25–29.9 kg/m2 | 40 | 56 | 67 | 182 | 28 (23 to 33) | 37 (29 to 47) | 76 (71 to 81) | 42 (32 to 52) | 73 (67 to 78) | 1.6 | 0.8 |
BMI ⩾30 kg /m2 | 52 | 81 | 41 | 136 | 43 (38 to 49) | 56 (46 to 66) | 63 (56 to 69) | 39 (32 to 48) | 77 (70 to 83) | 1.7 | 0.8 |
Non-consulter | 63 | 100 | 104 | 319 | 28 (24 to 32) | 38 (31 to 45) | 76 (72 to 80) | 39 (32 to 47) | 75 (71 to 79) | 1.6 | 0.8 |
Consulter | 42 | 54 | 29 | 77 | 48 (41 to 54) | 59 (48 to 70) | 59 (50 to 67) | 44 (34 to 54) | 73 (64 to 80) | 1.6 | 0.8 |