Frequency of genotypes expressing low levels of mannan-binding lectin (MBL) and C4AQ0 in five families after stratification for families with low MBL
| Patients with SLE, n = 14 (%) | First-degree relatives, n = 56(%) | Second-degree relatives, n = 16(%) | p* | p* | |
|---|---|---|---|---|---|
| MBL, mannan-binding lectin; SLE, systemic lupus erythematosus. | |||||
| *χ2 test for independence between patients with SLE, first-degree relatives and second-degree relatives. | |||||
| †χ2 test for trend between patients with SLE, first-degree relatives and second-degree relatives. | |||||
| Low MBL genotypes | 64 | 38 | 0 | <0.001 | <0.001 |
| C4AQ0 | 50 | 46 | 44 | 0.94 | 0.73 |
| Low MBL with C4AQ0 | 36 | 18 | 0 | 0.036 | 0.011 |