Table 6

 Occurrence of infections in four clinical trials of infliximab32–35 in systemic vasculitis (including patients with Wegener’s granulomatosis (WG))

InfectionOrganismComment
*The same patient had a similar episode 20 weeks after coming off infliximab. The skin ulcer and urinary tract infection occurred in the same individual.
Bronchopneumonia* Haemophilus influenzae Bronchiectasis requiring hospitalisation
Urinary sepsis Klebsiella Requiring hospitalisation; creatinine 425 μmol/l
Leg abscessMethicillin resistant Staphylococcus aureusSurgical drainage required
Endophthalmitis Nocardia Evisceration required
Skin ulcer Staphylococcus aureus Same patient
Urinary tract infection Escherichia coli