Table 3

 Sensitivity, specificity, and positive predictive value (PPV) of ACF, anti-CCP, and IgM-RF for the clinical diagnosis of rheumatoid arthritis in early arthritis

Sensitivity (%)Specificity (%)PPV (%)
ACF, antibodies to citrullinated human fibrinogen; CCP, cyclic citrullinated peptide; RF, rheumatoid factor; ROC, receiver operating characteristic.
Early arthritis (n = 379)
IgM-RF ⩾4544.696.796.6
ACF ⩾14055.892.694.1
Anti-CCP ⩾2557.894.295.5
IgM-RF negative early arthritis (n = 260)
ACF ⩾14028.794.987.2
Anti-CCP ⩾2530.896.691.7