Table 1

 Some angiogenesis inhibitors and their effect on HIF expression

Angiogenesis inhibitorHIF expression
*Related to RA.
ND, not determined; ↑, increased; ↓, reduced.
Endogenous inhibitors
Angiostatin*ND
Endostatin*
Troponin I*ND
IL4*ND
IL1Ra*ND
2-Methoxyoestradiol*ND
Exogenous inhibitors
Chloroquine*ND
Cyclo-oxygenase-2 inhibitors*↓ /−
Diclofenac
Fumigillin, AGM-1470, TNP-470*ND
GL-331
Glucocorticoids*↓ /↑
Gold compounds*ND
Ibuprofen
Ketorolac
Methotrexate*ND
Minocycline*ND
Penicillamine*ND
PX-478
SU5416
SulfasalazineND
Taxol*ND
Thalidomide*ND
TNFα inhibitors*ND
TX-402
VEGF inhibitorsND
YC-1