Table 3

Change in QoL scores (SF-36) in MSK disorder (n = 310) and MSK disorder-free (n = 620) groups over the follow up period

	MSK disorder				MSK disorder-free				p Value†	Difference in change
	Baseline		Follow up		Baseline		Follow up			Difference in change
	Mean*	95% CI	Mean*	95% CI	Mean*	95% CI	Mean*	95% CI		Mean ‡	95% CI	p Value§
*Mean scores adjusted for age, sex, living alone, and comorbidity (cancer and infectious disease), ranging from 0 (worst) to 100 (best).
†Baseline comparison between MSK disorder group and control group QoL means.
‡Change in mean score (baseline to follow up) in MSK disorder group minus change in mean score (baseline to follow up) in MSK disorder-free group.
§Test of interaction between time and group from a linear mixed model adjusted for age, sex, living alone, cancer, and infectious disease.
Physical functioning	94.5	92.3 to 96.7	92.8	90.6 to 95.0	94.5	92.3 to 96.7	94.0	91.9 to 96.2	0.95	−1.2	−2.6 to −0.01	0.047
Role physical	87.9	83.2 to 92.6	83.1	78.4 to 87.7	87.6	83.0 to 92.2	85.2	80.6 to 89.8	0.90	−2.4	−6.1 to 1.5	0.23
Bodily pain	85.4	81.5 to 89.4	75.4	71.5 to 79.4	86.3	82.4 to 90.2	83.7	79.8 to 87.6	0.49	−7.4	−10.1 to −4.5	<0.0001
Mental health	70.7	66.8 to 74.5	70.8	67.0 to 74.7	70.7	66.8 to 74.5	71.8	67.9 to 75.7	0.94	−1.0	−3.0 to 1.1	0.35
Role emotional	87.7	81.9 to 93.5	84.1	78.2 to 89.9	86.5	80.7 to 92.3	85.2	79.5 to 91.0	0.45	−2.3	−6.2 to 1.9	0.34
Social functioning	82.5	78.1 to 86.8	81.9	77.6 to 86.3	83.3	79.0 to 87.6	84.2	79.9 to 88.5	0.57	−1.5	−4.4 to 1.1	0.24
Vitality	66.8	63.3 to 72.0	65.9	62.0 to 69.7	66.5	62.6 to 70.3	68.2	64.3 to 72.0	0.69	−2.6	−4.8 to −0.9	0.005
General health	74.2	70.4 to 78.0	73.6	69.8 to 77.4	73.4	69.6 to 77.2	74.6	70.8 to 78.4	0.45	−1.8	−4.0 to −0.2	0.03
SF-6D utility score (×100)	77.5	75.2 to 79.8	76.4	74.1 to 78.7	78.0	75.6 to 80.3	77.8	75.5 to 80.1	0.54	−0.9	−2.4 to 0.42	0.17