Haemodynamic, myocardial perfusion, and strain rate values
| All patients with SSc (n = 18) | Diffuse cutaneous SSc (n = 10) | Limited cutaneous SSc (n = 8) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Baseline | Nifedipine | p Value | Baseline | Nifedipine | p Value | Baseline | Nifedipine | p Value | |
| MRI perfusion index | 0.19 (0.05) | 0.26 (0.07) | 0.0003 | 0.20 (0.05) | 0.26 (0.07) | 0.0078 | 0.17 (0.03) | 0.25 (0.07) | 0.01 |
| TDE systolic strain rates (s−1) | 1.5 (0.4) | 2.3 (0.6) | 0.0002 | 1.5 (0.5 ) | 2.3 (0.7) | 0.005 | 1.57 (0.42) | 2.28 (0.58) | 0.01 |
| TDE diastolic strain rates (s−1) | 3.0 (1.2) | 4.2 (1.6) | 0.0003 | 3.1 (1.4 ) | 4.2 (2.1) | 0.01 | 2.87 (1.03) | 4.09 (0.67) | 0.01 |
| Heart beats (/min) | 70 (13) | 75 (16) | 0.01 | 69 (12) | 74 (13) | 0.01 | 71 (15) | 75 (17) | 0.01 |
| Systolic arterial pressure (mm Hg) | 125 (21) | 122 (21) | NS | 124 (18) | 121 (14) | NS | 125 (23) | 123 (17) | NS |
| Diastolic arterial pressure (mm Hg) | 73 (12) | 70 (11) | NS | 72 (13) | 71 (9) | NS | 74 (13) | 71 (10) | NS |
| Systolic pressure-heart rate product | 8750 (273) | 9150 (336) | NS | 8556 (216) | 8591 (182) | NS | 8875 (225) | 9225 (289) | NS |