Genotype | In 100 white RA families | In families with anti-CCP+ RA cases | In families with AhFibA+ RA cases | ||||||
---|---|---|---|---|---|---|---|---|---|
RA | Controls | p Value | RA | Controls | p Value | RA | Controls | p Value | |
Haplotypes 3, 7, and 8 have been pooled for analysis as they correspond to the haplotype (GCC) conferring susceptibility to rheumatoid arthritis in the Japanese population. | |||||||||
AhFibA, anti-human fibrin(ogen) autoantibodies; CCP, cyclic citrullinated peptides; RA, rheumatoid arthritis. | |||||||||
NNGCC/NNGCC | 6 | 9 | 6 | 7 | 5 | 6 | |||
NNGCC/X | 31 | 21 | 20 | 15 | 18 | 12 | |||
X/X | 63 | 70 | 0.23 | 45 | 49 | 0.62 | 40 | 45 | 0.45 |