Table 2

 Carrier frequency of CARD15 variants in patients with spondyloarthropathies, Crohn’s disease, and controls (%)

Spondyloarthropathy (n = 104)Crohn’s disease (n = 156)Controls (n = 140)
R702WG908R1007fsOverall*R702WG908R1007fsOverall*R702WG908R1007fsOverall*
Data are numbers of patients carrying R702W, G908R or 1007fs variants.
CARD15−/+, heterozygous; CARD15−/−, homozygous.
Overall, total number of patients in the group carrying at least one variant.
*The sum of all allelic CARD15 variants is greater than the overall number of patients carrying at least one variant, as some patients carry two different single nucleotide polymorphisms, thus displaying compound heterozygous status.
CARD15 −/+ 12 (12)4 (4)4 (4)21 (20)39 (25)11 (7)27 (17)77 (49)18 (13)1 (1)6 (4)24 (17)
CARD15 −/− 0 (0)0 (0)1 (1)4 (3)3 (2)0 (0)0 (0)0 (0)0 (0)