Clinical response of patients with low, intermediate, and high pretreatment CRP levels
| Clinical response | Pretreatment CRP levels | Significance | ||
|---|---|---|---|---|
| Low (0–10 mg/l) | Intermediate (11–40 mg/l) | High (41–120 mg/l) | ||
| *Indicates statistical significance, NS indicates no statistical significance. | ||||
| GH, general health; SJC, swollen joint count; TJC, tender joint count. | ||||
| Mean DAS28, t = 0 | 5.3 | 6.2 | 6.8 | NS |
| Mean CRP, t = 0 | 4 | 23 | 68 | * |
| EULAR responders (%) | 74 | 74 | 71 | NS |
| Mean change in DAS28 | ||||
| 0–14 Weeks | −1.6 | −2.0 | −1.6 | NS |
| 0–2 Weeks | −0.9 | −1.3 | −1.5 | NS |
| 2–6 Weeks | −0.5 | −0.9 | −0.6 | NS |
| 6–14 Weeks | −0.2 | 0.2 | 0.6 | * |
| Mean change in ESR (mm/1st h) 6–14 weeks | −1 | 4 | 8 | * |
| Mean change in GH (mm) 6–14 weeks | −5 | 5 | 15 | * |
| Mean change in SJC 6–14 weeks | 0 | 0 | 3 | * |
| Mean change in TJC 6–14 weeks | −1 | 0 | 3 | * |