Table 1

 Clinical response of patients with low, intermediate, and high serum trough infliximab levels at 14 weeks

Clinical responseSerum trough infliximab levels at 14 weeks
Low (0–1.2 mg/l)Intermediate (1.3–4.7 mg/l)High (5.0–25.8 mg/l)Significance
*Indicates statistical significance, NS indicates no statistical significance.
Mean DAS28, t = 06.46.15.8NS
Mean CRP, t = 0492917*
EULAR responders (%)509088*
Mean change in DAS28 between
    0–2 Weeks−1.3−1.2−1.1NS
    2–6 Weeks−0.4−0.7−1.0NS
    6–14 Weeks0.9−0.1−0.2*
    0–14 Weeks−0.9 (−1.4)−2.0 (−1.3)−2.4 (−1.4)*